What is PDG?

The procedure has been designed and tested to help couples reduce the risk of conceiving a child in situations where there is a high risk of a chromosome or genetic disorder.

  • Preimplantation Genetic Diagnosis (PGD) is the technique of checking the genes or chromosomes for a specific genetic condition.
  • Like PGS testing, PGD is also used in parallel with an IVF treatment cycle.  A small number of cells are removed from the blastocyst embryo and sent to the genetic lab for testing. 
  • There are over 100 known genetic disorders that can be tested.  For some couples with a less common genetic disorder, the genetics lab can perform feasibility testing to ascertain if a test can be developed for their specific disorder.

Who is suitable for PGD testing?

  • Carriers of sex-linked genetic disorders
  • Carriers of single gene disorders
  • Carriers of translocations

Preimplantation genetic diagnosis involves using assisted reproductive technology also known as ART, a system also used to assist couples with fertility problems. ART is a very delicate and complicated procedure that considerably increases successful problem free child development during and after pregnancy.

The procedure is used six days subsequent to egg collection. New embryos are given six days to develop at which point several cells are selected and removed from each embryo for testing. During these tests doctors will carry out investigations into the chromosomes or DNA in order to determine whether or not there are any chromosome or genetic abnormalities evident.

Once tests have revealed the strongest embryos with no chromosome or genetic abnormalities, these embryos will be transferred to the uterus. At this stage of the procedure the desired outcome is for the embryos to implant and as a result of implantation pregnancy follows. Using this procedure the baby will be free of all disorders tested for subsequent to day six of fertilization.